Molecular group:
Adhesion molecules
Molecule/Cell:
CD11d/CD18
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
10^5
Mouse genetic background (Con):
129/Sv x C57BL/6
Level of backcrossing:
N.I.
Experimental treatment group (EG):
aD -/-
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
CM (~75%)
Pathology (EG):
CM (~50%)
Parasitemia (EG vs Con):
Similar
Additional phenotypes (EG vs Con):
Similar anemia; ↓ serum IL-12p40
Refs:
Miyazaki et al., 2007, J Immunol
Hyperlink: