Molecular group:
Adhesion molecules
Molecule/Cell:
CD11a/CD18 (LFA-1)
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
10^7
Mouse genetic background (Con):
CBA/J
Experimental treatment group (EG):
anti-CD11a
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
CM
Pathology (EG):
No CM
Parasitemia (EG vs Con):
N.I.
Additional phenotypes (EG vs Con):
↓ platelet sequestration in brain and similar platelet sequestration in lung
Refs:
Grau et al., 1993, Eur Cytokine Netw
Hyperlink: