Molecular group:
Adhesion molecules
Molecule/Cell:
CD11b/CD18 (Mac-1, CR3)
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
5
Mouse genetic background (Con):
C57BL/6
Level of backcrossing:
N.I.
Experimental treatment group (EG):
CR3 -/-
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
CM (~90%)
Pathology (EG):
CM (~80%)
Parasitemia (EG vs Con):
Increased
Additional phenotypes (EG vs Con):
N.I.
Refs:
Ramos et al., 2012, Parasite Immunol
Hyperlink: