Big endothelin-1 (bET1)

Molecular group: 
Neural or endothelial cell stress/damage/activation markers
Molecule/Cell: 
Big endothelin-1 (bET1)
Plasmodium strain: 
Plasmodium falciparum
Organ: 
Plasma
Population: 
Thailand
Transmission: 
Unstable
Adult/Pediatric: 
Adult
CM vs NCSM: 
=
Patient number: 
54
Additional differences: 
SM > NM, HC; plasma concentrations remained elevated during first 7 days post treatment (sustained endothelial cell damage ??); + correlation with plasma TNF-a; - correlation with platelet count; no difference between patients with and without renal failure
Refs: 
Wenisch et al., 1996, J Infect Dis